BDBM517392 US11104690, Example 187::methyl 4-{3-(2- chlorophenyl)-6-[(3-methyl- 1,1- dioxidotetrahydrothiophen-3- yl)carbamoyl]-1H-indazol-1- yl}benzoate (racemic)

SMILES COC(=O)c1ccc(cc1)-n1nc(-c2ccccc2Cl)c2ccc(cc12)C(=O)NC1(C)CCS(=O)(=O)C1

InChI Key InChIKey=DIKUYWCBKNPDHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517392   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517392(US11104690, Example 187 | methyl 4-{3-(2- chloroph...)
Affinity DataIC50: 644nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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