BDBM518780 (4-((4- (cyclopropylamino)- 3- (trifluoromethyl)- 1-((2- (trimethylsilyl) ethoxy)methyl)- 1H-pyrrolo[2,3- b]pyridin-6-yl)3- methoxyphenyl) (4- morpholino- piperidine-1- yl)methanone::US11117892, Example 94
SMILES COc1cc(ccc1Nc1cc(NC2CC2)c2c(c[nH]c2n1)C(F)(F)F)C(=O)N1CCC(CC1)N1CCOCC1
InChI Key InChIKey=RBTKOQCREJDPQN-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 518780
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 55nMAssay Description:Table 5: Particularly, a substrate was added to a basic reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, ...More data for this Ligand-Target Pair