BDBM518911 US11116757, No. A206

SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(Cc3cc(F)c(F)c(F)c3)CC2)cc(c1)C(F)(F)F

InChI Key InChIKey=BKEFMLYJOSZEMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518911   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
Memorial Sloan Kettering Cancer Center

US Patent
LigandChemical structure of BindingDB Monomer ID 518911BDBM518911(US11116757, No. A206)
Affinity DataIC50: 2.09E+4nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent