BDBM519829 1,1,1,3,3,3- Hexafluoropropan- 2-yl 1-(quinolin- 2-ylmethyl)- 1,8-diazaspiro [4.5]decane-8- carboxylate::US11142526, Example 54

SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc3ccccc3n2)CC1)C(F)(F)F

InChI Key InChIKey=JYXKOHKQTRHHHH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519829   

TargetMonoglyceride lipase(Mouse)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 519829BDBM519829(1,1,1,3,3,3- Hexafluoropropan- 2-yl 1-(quinolin- 2...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were administered to wild-type C57B1/6J by oral gavage in a vehicle of polyethylene glycol. Each animal was sacrificed 4 h following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent