BDBM519947 1,1,1,3,3,3- Hexafluoropropan- 2-yl 4-(2,2- difluoro-2-(5- methoxypyrazin- 2-yl)-N- methylacetamido)-4- methylpiperidine-1- carboxylate::US11142526, Example 199

SMILES COc1cnc(cn1)C(F)(F)C(=O)N(C)C1(C)CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=MDDBULAETCSAOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519947   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM519947(1,1,1,3,3,3- Hexafluoropropan- 2-yl 4-(2,2- difluo...)
Affinity DataIC50: 100nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent