BDBM522050 N-[1-(cyanomethyl)-3-[6- (difluoromethoxy)-3,4- dihydro-2H-1,4-benzothiazin- 7-yl]pyrazol-4- yl]pyrazolo[1,5-a]pyrimidine- 3-carboxamide::US11155557, Example 140
SMILES FC(F)Oc1cc2NCCSc2cc1-c1nn(CC#N)cc1NC(=O)c1cnn2cccnc12
InChI Key InChIKey=KBUFRYLIBNBLOU-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 522050
Affinity DataKi: 0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair