BDBM522315 US11161839, Example 12b

SMILES C[C@H](Nc1nc(=O)n(C)c2ccc(Nc3nc(ncc3Cl)N3CCC(CC3)C(=O)N(C)C)cc12)C1CC1

InChI Key InChIKey=PEIIHFMXMOKAMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 522315   

TargetB-cell lymphoma 6 protein [5-129](Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 522315BDBM522315(US11161839, Example 12b)
Affinity DataIC50: 302nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent