BDBM52237 2-methyl-7-[phenyl-(2-pyridinylamino)methyl]-8-quinolinol::2-methyl-7-[phenyl-(2-pyridylamino)methyl]quinolin-8-ol::2-methyl-7-[phenyl-(pyridin-2-ylamino)methyl]quinolin-8-ol::MLS000522853::Oxyquinoline, D2, #5::SMR000128119::cid_4999481

SMILES Cc1ccc2ccc(C(Nc3ccccn3)c3ccccc3)c(O)c2n1

InChI Key InChIKey=JXFRSLRXSBGCHN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 52237   

TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute of Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM52237(2-methyl-7-[phenyl-(pyridin-2-ylamino)methyl]quino...)
Affinity DataIC50: 700nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Weill Medical College of Cornell University

LigandPNGBDBM52237(2-methyl-7-[phenyl-(pyridin-2-ylamino)methyl]quino...)
Affinity DataIC50: 7.00E+3nMAssay Description:The predication of no specific interaction between enzyme and iron-binding inhibitors but the Enzyme inhibition constants (IC50s)will change in paral...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2011
Entry Details Article
PubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM52237(2-methyl-7-[phenyl-(pyridin-2-ylamino)methyl]quino...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay