BDBM522377 US11161839, Example 25a

SMILES C[C@H]1CN(C[C@@H](C)C1(F)F)c1ncc(Cl)c(Nc2ccc3n(C)c(=O)nc(NC(C)(C)c4ncccn4)c3c2)n1

InChI Key InChIKey=VFZCYSUMYUKYSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 522377   

TargetB-cell lymphoma 6 protein [5-129](Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandChemical structure of BindingDB Monomer ID 522377BDBM522377(US11161839, Example 25a)
Affinity DataIC50: 186nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent