BDBM523910 US11136329, Compound 12::ethyl 4-((7-(thiophen-3- ylmethyl)-7H-pyrrolo[2,3- d]pyrimidin-2- yl)amino)benzoate

SMILES CCOC(=O)c1ccc(Nc2ncc3ccn(Cc4ccsc4)c3n2)cc1

InChI Key InChIKey=PQUIUTUIUKMMBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523910   

TargetTyrosine-protein kinase JAK3(Human)
Vimalan Biosciences

US Patent
LigandPNGBDBM523910(US11136329, Compound 12 | ethyl 4-((7-(thiophen-3-...)
Affinity DataIC50: 550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent