BDBM523921 US11136329, Compound 21::ethyl 2-(4-((7-isopentyl- 7H-pyrrolo[2,3- d]pyrimidin-2-yl)amino)- 1H-pyrazol-1-yl)acetate

SMILES CCOC(=O)Cn1cc(Nc2ncc3ccn(CCC(C)C)c3n2)cn1

InChI Key InChIKey=QJYKJBWJJXYGPX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 523921   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523921(US11136329, Compound 21 | ethyl 2-(4-((7-isopentyl...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523921(US11136329, Compound 21 | ethyl 2-(4-((7-isopentyl...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523921(US11136329, Compound 21 | ethyl 2-(4-((7-isopentyl...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523921(US11136329, Compound 21 | ethyl 2-(4-((7-isopentyl...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent