BDBM523948 US11136329, Compound 44::ethyl 2-(3-((7-(2- ethylbutyl)-7H-pyrrolo[2,3- d]pyrimidin-2-yl)amino)- 1H-pyrazol-1-yl)acetate

SMILES CCOC(=O)Cn1ccc(Nc2ncc3ccn(CC(CC)CC)c3n2)n1

InChI Key InChIKey=YWDIUMSOPSPLEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 523948   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523948(US11136329, Compound 44 | ethyl 2-(3-((7-(2- ethyl...)
Affinity DataIC50:  5.50E+3nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523948(US11136329, Compound 44 | ethyl 2-(3-((7-(2- ethyl...)
Affinity DataIC50:  550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523948(US11136329, Compound 44 | ethyl 2-(3-((7-(2- ethyl...)
Affinity DataIC50:  550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523948(US11136329, Compound 44 | ethyl 2-(3-((7-(2- ethyl...)
Affinity DataIC50:  550nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent