BDBM523984 US11136329, Compound 93::isopropyl 2-(4-((7-(2- ethylbutyl)-7H- pyrrolo[2,3-d]pyrimidin- 2-yl)amino)-1H-pyrazol- 1-yl)acetate

SMILES CCC(CC)Cn1ccc2cnc(Nc3cnn(CC(=O)OC(C)C)c3)nc12

InChI Key InChIKey=IYFVMPUYAZSCSB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 523984   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523984(US11136329, Compound 93 | isopropyl 2-(4-((7-(2- e...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523984(US11136329, Compound 93 | isopropyl 2-(4-((7-(2- e...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523984(US11136329, Compound 93 | isopropyl 2-(4-((7-(2- e...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Vimalan Biosciences

US Patent
LigandPNGBDBM523984(US11136329, Compound 93 | isopropyl 2-(4-((7-(2- e...)
Affinity DataIC50: <100nMAssay Description:10 mM test compound stock or 1 mM control compound stock (tofocitinib, ruxolitinib or staurosporine) in DMSO was diluted to 0.4 mM in DMSO. A 3-fold ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent