BDBM524546 US11168089, Ex. No. 22::US11873304, Example 22

SMILES Nc1nc(cc2nc(Cc3c(F)cccc3CN[C@H]3CCNC3=O)nn12)-c1cccc(C#N)c1F

InChI Key InChIKey=CRCLTXHRWVYQDZ-SFHVURJKSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 524546   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM524546(US11168089, Ex. No. 22 | US11873304, Example 22)
Affinity DataKi: <10nMAssay Description:Assays were conducted in black low volume 384-well polystyrene plates (Greiner 784076-25) in a final volume of 10 μL. Test compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM524546(US11168089, Ex. No. 22 | US11873304, Example 22)
Affinity DataKi: <10nMAssay Description:Assays were conducted in black low volume 384-well polystyrene plates (Greiner 784076-25) in a final volume of 10 μL. Test compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM524546(US11168089, Ex. No. 22 | US11873304, Example 22)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent