BDBM525007 US11168095, Example 142

SMILES C[C@H]1CCCn2cnnc2-c2cccc(NC(=O)c3cc(ccc3O1)N1CCOCC1)n2

InChI Key InChIKey=CCHVBLDYLBVHBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525007   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM525007(US11168095, Example 142)
Affinity DataIC50: 100nMAssay Description:Table 2: Alternatively, the protein kinase activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Cor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent