BDBM525169 Benzyl N-[(1S)-1-[[(2-chloroacetyl)-[(2-oxo-pyrrolidin-3-yl)methyl]amino]carbamoyl]-3-methyl-butyl]carbamate::WO2022043374, Example 18

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NN(CC1CCNC1=O)C(=O)CCl

InChI Key InChIKey=BRRFTKVQMJBDFI-DJNXLDHESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525169   

TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

Curated by ChEMBL
LigandPNGBDBM525169(Benzyl N-[(1S)-1-[[(2-chloroacetyl)-[(2-oxo-pyrrol...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant SARS-CoV-2 3CLpro expressed in Escherichia coli BL21 DE3 using FAM-KTSAVLQSGFRKMEK-TAMRA fluorogenic peptide as substrate p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
A*Star

Curated by ChEMBL
LigandPNGBDBM525169(Benzyl N-[(1S)-1-[[(2-chloroacetyl)-[(2-oxo-pyrrol...)
Affinity DataIC50:  17nMAssay Description:For the SARS-CoV-2 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV-2 3CL protease were mixed with serial dilutions of each c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed