BDBM529869 US11203591, Example 275

SMILES CC(C)n1cnc2cc(nc(Nc3cc(C(=O)NCC(F)F)c(Cl)c(F)c3F)c12)-c1ccc2c(c1)N(C(=O)C21CC1)C1(C)CC(C1)N1CCCCC1

InChI Key InChIKey=RBYFYKRBFVWVRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529869   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM529869(US11203591, Example 275)
Affinity DataIC50: 0.0600nMAssay Description:Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent