BDBM530163 US11203600, Example 244::[3,3-difluoro-1-(5- fluoropyrimidin-2- yl)-4-methyl-4- piperidyl]-(3,5- dihydro-2H- pyrido[3,4- f][1,4]oxazepin-4- yl)methanone

SMILES CC1(CCN(CC1(F)F)c1ncc(F)cn1)C(=O)N1CCOc2ccncc2C1

InChI Key InChIKey=MQGUWUKFWCYJJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530163   

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM530163([3,3-difluoro-1-(5- fluoropyrimidin-2- yl)-4-methy...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1 [8-327](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM530163([3,3-difluoro-1-(5- fluoropyrimidin-2- yl)-4-methy...)
Affinity DataIC50: 100nMAssay Description:Test compounds were serially diluted in DMSO at 100 fold final concentrations in the assay (1% DMSO final). In each well of a 384-well Plate were dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent