BDBM530292 WO2022064009, Compound 53::WO2022064009, Compound 68

SMILES C[C@@H]1Cc2cnc(NC[C@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1

InChI Key InChIKey=IPTCAPBTKXTALM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 530292   

LigandChemical structure of BindingDB Monomer ID 530292BDBM530292(WO2022064009, Compound 68 | WO2022064009, Compound...)
Affinity DataIC50: 10nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530292BDBM530292(WO2022064009, Compound 68 | WO2022064009, Compound...)
Affinity DataIC50: 14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530292BDBM530292(WO2022064009, Compound 68 | WO2022064009, Compound...)
Affinity DataIC50: 41nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009