BDBM530319 WO2022064009, Compound 83::WO2022064009, Compound 89

SMILES CC(C)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1

InChI Key InChIKey=PIEQRGANCWMOJQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 530319   

LigandChemical structure of BindingDB Monomer ID 530319BDBM530319(WO2022064009, Compound 89 | WO2022064009, Compound...)
Affinity DataIC50: 200nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530319BDBM530319(WO2022064009, Compound 89 | WO2022064009, Compound...)
Affinity DataIC50: 200nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530319BDBM530319(WO2022064009, Compound 89 | WO2022064009, Compound...)
Affinity DataIC50: 794nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530319BDBM530319(WO2022064009, Compound 89 | WO2022064009, Compound...)
Affinity DataIC50: 794nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009