BDBM530404 WO2022064009, Compound 192

SMILES CO[C@H]1CC[C@H](Nc2ncc3c(n2)CN(C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)C2(CC2)C3)CC1

InChI Key InChIKey=YMHSMVVOGVDKAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530404   

LigandChemical structure of BindingDB Monomer ID 530404BDBM530404(WO2022064009, Compound 192)
Affinity DataIC50: 145nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530404BDBM530404(WO2022064009, Compound 192)
Affinity DataIC50: 158nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009