BDBM531781 6-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)-N-[3-(4-fluorophenyl)-1-(2-methoxyethyl)-4-methyl-1H-pyrazol-5-yl]pyrimidin-4-amine::US11208400, Example 414

SMILES CC1(C)CCC(CN2CC(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)=C(c2ccc(F)cc2)C1

InChI Key InChIKey=KOIPLLMRBPWFOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531781   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531781BDBM531781(3-(5-((1-((4'-fluoro-5,5-dimethyl-3,4,5,6- tetrahy...)
Affinity DataIC50: 760nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent