BDBM5322 1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indole::3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3e

SMILES C(CN1CCCCC1)Cn1cc(-c2cncc(c2)-c2ccsc2)c2ccccc12

InChI Key InChIKey=ARVPXHGQLZVIJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5322   

TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5322(1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)p...)
Affinity DataIC50: 38nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5322(1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)p...)
Affinity DataIC50: 38nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed