BDBM532270 6-[4-[(4-Fluorophenyl)methylsulfonyl]-2-(trifluoromethyl)piperazin-1-yl]-4-[2-[(2-methylpyrimidin-4-yl)amino]-4-pyridyl]-1H-pyridin-2-one::US11208423, Example 33::US11780858, Example 33
SMILES Cc1nccc(Nc2cc(ccn2)-c2cc([nH]c(=O)c2)N2CCN(CC2C(F)(F)F)S(=O)(=O)Cc2ccc(F)cc2)n1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 532270
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience
US Patent
Sprint Bioscience
US Patent
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Sprint Bioscience
US Patent
Sprint Bioscience
US Patent
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair