BDBM533406 (2R,3S,4R,5R)-2-((R)-(4- chlorophenyl)(hydroxy)methyl)-5-(6- hydrazineylidene-3,6-dihydro-9H-purin-9- yl)tetrahydrofuran-3,4-diol::US11220524, Example 39

SMILES N/N=c1/nc[nH]c2c1ncn2[C@@H]1O[C@H]([C@H](O)c2ccc(Cl)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=INQRYZHNGDLKHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533406   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 533406BDBM533406(US11220524, Example 39 | (2R,3S,4R,5R)-2-((R)-(4- ...)
Affinity DataIC50: 180nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent