BDBM533436 7-((2R,3R,4S)-5-((R)-1-(4-chlorophenyl)- 2,2,2-trifluoro-1-hydroxyethyl)-3,4- dihydroxytetrahydrofuran-2-yl)-1,7-dihydro- 4H-pyrrolo[2,3-d]pyrimidin-4-one O-methyl oxime::US11220524, Example 79

SMILES CO/N=c1\nc[nH]c2c1ccn2[C@@H]1OC([C@](O)(c2ccc(Cl)cc2)C(F)(F)F)[C@@H](O)[C@H]1O

InChI Key InChIKey=AUTVDFCZSXFZSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533436   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 533436BDBM533436(US11220524, Example 79 | 7-((2R,3R,4S)-5-((R)-1-(4...)
Affinity DataIC50: 6.46E+3nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent