BDBM533505 US11220518, Ex. No. M2::US11780853, Example M2

SMILES CCOc1ccnc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1

InChI Key InChIKey=LROJDATVWNTLOA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533505   

TargetProtein kinase C beta type Isoform 2(Human)
Pfizer

US Patent
LigandPNGBDBM533505(US11220518, Ex. No. M2 | US11780853, Example M2)
Affinity DataKi:  16.1nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM533505(US11220518, Ex. No. M2 | US11780853, Example M2)
Affinity DataKi:  16.1nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent