BDBM533517 US11220509, Example 140

SMILES OC(=O)c1cn2c(NCc3c4CCOc4ccc3F)ncc(C3CCNCC3)c2n1

InChI Key InChIKey=AQEHGQLBCAFNCH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533517   

TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Human)
Mirati Therapeutics

US Patent

LigandBDBM533517(US11220509, Example 140)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/14/2022
Entry Details
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