BDBM533604 US11220509, Example 228::US11485738, Example 228::US20240398811, Example 228

SMILES Cc1cc(-c2cnc(NCc3c4OCOc4ccc3F)n3cc(nc23)C#N)n(C)n1

InChI Key InChIKey=FOBKSISMMONNAI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 533604   

LigandChemical structure of BindingDB Monomer ID 533604BDBM533604(US11220509, Example 228 | US11485738, Example 228 ...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 533604BDBM533604(US11220509, Example 228 | US11485738, Example 228 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 533604BDBM533604(US11220509, Example 228 | US11485738, Example 228 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 533604BDBM533604(US11220509, Example 228 | US11485738, Example 228 ...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 533604BDBM533604(US11220509, Example 228 | US11485738, Example 228 ...)
Affinity DataIC50: 300nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent