BDBM533977 WO2022081807, Example 84

SMILES CCc1cccc(OC(C)C)c1S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1

InChI Key InChIKey=ASALMTIPHBIIGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533977   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 533977BDBM533977(WO2022081807, Example 84)
Affinity DataIC50: 43nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
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Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807