BDBM533986 WO2022081807, Example 93::[3-sulfamoyl-4-(trifluoromethoxy)phenyl]methyl 6-(azetidin-1-yl)-4-fluoro-1-benzofuran-2-carboxylate

SMILES NS(=O)(=O)c1cc(OC(=O)c2cc3c(F)cc(cc3o2)N2CCC2)ccc1OC(F)(F)F

InChI Key InChIKey=MFWLLDGCXWGPQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533986   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 533986BDBM533986(WO2022081807, Example 93 | [3-sulfamoyl-4-(trifluo...)
Affinity DataIC50: 1.16E+3nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807