BDBM533998 Methyl {[1-{2-[(2-ethoxybenzene-1-sulfonyl)carbamoyl]-4-fluoro-1-benzofuran-6-yl}azetidin-2-yl]methyl}carbamate (rac)::WO2022081807, Example 105

SMILES CCOc1ccccc1S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1CNC(=O)OC

InChI Key InChIKey=UXBZHRRRQTVALR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533998   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 533998BDBM533998(WO2022081807, Example 105 | Methyl {[1-{2-[(2-etho...)
Affinity DataIC50: 1.12E+3nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807