BDBM534002 N-(2,3-dihydro-1,4-benzodioxine-5-sulfonyl)-4-fluoro-6-(3-fluoroazetidin-1-yl)-1-benzofuran-2-carboxamide::WO2022081807, Example 109

SMILES FC1CN(C1)c1cc(F)c2cc(oc2c1)C(=O)NS(=O)(=O)c1cccc2OCCOc12

InChI Key InChIKey=SXBGCCGKZYBBJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534002   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534002BDBM534002(WO2022081807, Example 109 | N-(2,3-dihydro-1,4-ben...)
Affinity DataIC50: 172nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807