BDBM534022 6-(Azetidin-1-yl)-4-fluoro-N-{2-[(propan-2-yl)oxy]benzene-1-sulfonyl}-1-benzofuran-2-carboxamide::WO2022081807, Example 129

SMILES CC(C)Oc1ccccc1S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1

InChI Key InChIKey=QYBIFVXALJAWQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534022   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534022BDBM534022(WO2022081807, Example 129 | 6-(Azetidin-1-yl)-4-fl...)
Affinity DataIC50: 36nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534022BDBM534022(WO2022081807, Example 129 | 6-(Azetidin-1-yl)-4-fl...)
Affinity DataIC50: 52nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807