BDBM534118 6-(Azetidin-1-yl)-N-[(2-(benzyloxy)-5-(tert-butyl)phenyl]sulfonyl)-4-fluorobenzofuran-2-carboxamide::WO2022081807, Example 225

SMILES CC(C)(C)c1ccc(OCc2ccccc2)c(c1)S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1

InChI Key InChIKey=XGDLXRKSCLTAJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534118   

TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534118(6-(Azetidin-1-yl)-N-[(2-(benzyloxy)-5-(tert-butyl)...)
Affinity DataIC50:  9.82nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534118(6-(Azetidin-1-yl)-N-[(2-(benzyloxy)-5-(tert-butyl)...)
Affinity DataIC50:  3.72nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed