BDBM534128 N-([1,1'-biphenyl]-2-sulfonyl)-6-(pyridin-3-yl)-1-benzofuran-2-carboxamide ::WO2022081842, Example 4

SMILES O=C(NS(=O)(=O)c1ccccc1-c1ccccc1)c1cc2ccc(cc2o1)-c1cccnc1

InChI Key InChIKey=PVVUZHMGSNISLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534128   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534128BDBM534128(WO2022081842, Example 4 | N-([1,1'-biphenyl]-2-sul...)
Affinity DataIC50: 1.52E+4nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534128BDBM534128(WO2022081842, Example 4 | N-([1,1'-biphenyl]-2-sul...)
Affinity DataIC50: 2.00E+4nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842