BDBM534132 N2-([1,1'-biphenyl]-2-sulfonyl)-N6,N6-dimethyl-1-benzofuran-2,6-dicarboxamide ::WO2022081842, Example 8

SMILES CN(C)C(=O)c1ccc2cc(oc2c1)C(=O)NS(=O)(=O)c1ccccc1-c1ccccc1

InChI Key InChIKey=XLEFOSSAQPYZJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534132   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534132BDBM534132(WO2022081842, Example 8 | N2-([1,1'-biphenyl]-2-su...)
Affinity DataIC50: 1.73E+4nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534132BDBM534132(WO2022081842, Example 8 | N2-([1,1'-biphenyl]-2-su...)
Affinity DataIC50: 2.00E+4nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842