BDBM534184 N-(2,4-Dichlorobenzenesulfonyl)-6-(propan-2-yl)-1-benzofuran-2-carboxamide::WO2022081842, Example 57

SMILES CC(C)c1ccc2cc(oc2c1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=WAHZHKYIPHCCLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534184   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534184BDBM534184(WO2022081842, Example 57 | N-(2,4-Dichlorobenzenes...)
Affinity DataIC50: 611nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534184BDBM534184(WO2022081842, Example 57 | N-(2,4-Dichlorobenzenes...)
Affinity DataIC50: 5.25E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842