BDBM534259 WO2022081973, Example 63::[(2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl 3-dodecylsulfanylpropyl hydrogen phosphate (63)

SMILES CCCCCCCCCCCCSCCCOP(O)(=O)OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)c1ccc2c(N)ncnn12

InChI Key InChIKey=CKFCOHIQVKDKFH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534259   

TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Gilead Sciences

WIPO
LigandPNGBDBM534259(WO2022081973, Example 63 | [(2R,3S,4R,5R)-5-(4-Ami...)
Affinity DataEC50:  470nMAssay Description:Antiviral activity of compounds against SARS-CoV-2 is evaluated as described in Xue, Xi et al.2020. Briefly, the human alveolar epithelial cell line ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081973

TargetReplicase polyprotein 1ab(2019-nCoV)
Gilead Sciences

WIPO
LigandPNGBDBM534259(WO2022081973, Example 63 | [(2R,3S,4R,5R)-5-(4-Ami...)
Affinity DataEC50:  1.00E+4nMAssay Description:Antiviral activity of compounds against SARS-CoV-2 is evaluated as described in Xue, Xi et al.2020. Briefly, the human alveolar epithelial cell line ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081973