BDBM535106 Preparation of 5-fluoro-N-((5-fluoro-2-(2-(trifluoromethyl)pyrimidin-5-yl)pyridin-4-yl)methyl)-2-(4-fluorophenylsulfonyl)-2-aza-bicyclo[2.2.1]heptane-3-carboxamide::US11236046, Example 185

SMILES FC1CC2CC1C(N2S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(ncc1F)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=FVXQEVATGMMNBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535106   

LigandPNGBDBM535106(Preparation of 5-fluoro-N-((5-fluoro-2-(2-(trifluo...)
Affinity DataIC50: 155nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent