BDBM535237 US11236047, Example 67::US11236047, Example 68

SMILES CN1CCN(CC(C)(O)c2cc3C(=O)N(Cc4ccc(Cl)cc4S(C)(=O)=O)[C@](OC4CCOC4)(c3c(F)c2)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=GEZPZMXREXHEJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 535237   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535237BDBM535237(US11236047, Example 67 | US11236047, Example 68)
Affinity DataIC50: 1.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535237BDBM535237(US11236047, Example 67 | US11236047, Example 68)
Affinity DataIC50: 7nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535237BDBM535237(US11236047, Example 67 | US11236047, Example 68)
Affinity DataIC50: 29nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent