BDBM535247 6-{[(1R)-1-(4-chlorophenyl)-7-fluoro- 1-[(cis-3-hydroxycyclobutyl)methoxy]- 5-(2-hydroxypropan-2-yl)-3-oxo-2,3- dihydro-1H-isoindol-2- yl]methyl}pyridine-3-carbonitrile::US11236047, Example 81::US20230338337, Example 81
SMILES CN1CCC(CC1)C(C)(O)c1cc2C(=O)N(Cc3ccc(Cl)cc3S(C)(=O)=O)[C@](OCC3(CO)CC3)(c2c(F)c1)c1ccc(Cl)cc1
InChI Key InChIKey=MNUHQOFWGYDTKI-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 535247
Affinity DataIC50: 2.60nMAssay Description:Each assay was performed in a final volume of 15 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair