BDBM535343 US11236047, Example 171::US11236047, Example 172

SMILES C[S+]([O-])C1(CO[C@]2(N(Cc3ccc(Cl)cn3)C(=O)c3cc(cc(F)c23)C(C)(C)O)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=BMDCWINLUAOPGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 535343   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535343BDBM535343(US11236047, Example 171 | US11236047, Example 172)
Affinity DataIC50: 130nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535343BDBM535343(US11236047, Example 171 | US11236047, Example 172)
Affinity DataIC50: 140nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent