BDBM535743 US11236047, Example 333

SMILES CCC(O)(c1cscn1)c1cc2C(=O)N(Cc3ccc(cn3)C#N)[C@](OCCO)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=XIIWYJNBDQFHIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535743   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535743BDBM535743(US11236047, Example 333)
Affinity DataIC50: 4.40nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent