BDBM535754 7'-(2-Methylpyridin-4-yl)-2'- oxo-1',4'-dihydro-2'H- spiro$#9484;pyrrolidine-3,3'- quinoline$#9488;-1-carbonitrile::US11236092, Example 131::US11236092, Example 34

SMILES Cc1cc(ccn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key InChIKey=XRVQQNQHGBMAJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 535754   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535754BDBM535754(US11236092, Example 131 | 7'-(2-Methylpyridin-4-yl...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535754BDBM535754(US11236092, Example 131 | 7'-(2-Methylpyridin-4-yl...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent