BDBM536516 (S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylpiperazin-1- yl)-2-fluoropyridin-4- yl)amino)-2-oxo- ethyl)-4-oxo-4,6,7,8- tetrahydro-1H- dipyrrolo[1,2-a:2',3'-d] pyrimidin-3-yl)-2- hydroxy-4-methoxy- benzamide::US11242351, Compound I-95

SMILES COc1c(Cl)c(O)c(cc1-c1cn(CC(=O)Nc2cc(nc(F)c2Cl)N2CCN(C)C[C@@H]2C)c2nc3CCCn3c(=O)c12)C(N)=O

InChI Key InChIKey=PBGPTBJLOKADHP-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536516   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandChemical structure of BindingDB Monomer ID 536516BDBM536516((S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylp...)
Affinity DataKd:  450nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent