BDBM536874 N-methyl-1-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)-3-morpholino-4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxamide::US11247989, Example 48

SMILES CNC(=O)N1CCc2c(C1)n(nc2N1CCOCC1)-c1cccc2cc(ncc12)-c1cnn(C)c1

InChI Key InChIKey=VRVMHHGGFDAADO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536874   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 536874BDBM536874(N-methyl-1-(3-(1-methyl-1H-pyrazol-4-yl)isoquinoli...)
Affinity DataIC50: 9.61nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent