BDBM536877 1-(3-(2-(pyridin-3-yl)-1H-benzo[d]imidazol-4-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one::US11247989, Example 51

SMILES CC(=O)N1CCc2c(c(-c3cccc4[nH]c(-c5cccnc5)nc34)nn2C2CCOCC2)C1

InChI Key InChIKey=KRSNMXSWHQJHSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536877   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 536877BDBM536877(1-(3-(2-(pyridin-3-yl)-1H-benzo[d]imidazol-4-yl)-1...)
Affinity DataIC50: 121nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent