BDBM537170 US11247989, Example 150

SMILES COc1ccc(-c2cn3cccc(-c4nn(C5CCOCC5)c5CCN(Cc45)C(C)=O)c3n2)c(F)c1

InChI Key InChIKey=PQZNFEGYHZKADZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537170   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 537170BDBM537170(US11247989, Example 150)
Affinity DataIC50: 66.7nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent