BDBM537186 US11247989, Example 166

SMILES CC(=O)N1CCc2c(C1)c(nn2C1CCOC1)-c1cccc(c1)C(=O)Nc1ncc(-c2ccccc2)n1C

InChI Key InChIKey=XHLPQIVZNMBBGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537186   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 537186BDBM537186(US11247989, Example 166)
Affinity DataIC50: 36.5nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent